A team of doctors embark on a local mission in the Amazon rain forest, but it soon becomes clear that not everybody - or everything - is happy to see them. Their sudden appearance draws the attention of an animal predator, the "Boiúna."
Grace, a writer and young mother, is slowly slipping into madness. Locked away in an old house in and around Montana, we see her acting increasingly agitated and erratic, leaving her companion, Jackson, increasingly worried and helpless.